REDUCED MITOCHONDRIAL PYRUVATE COPYRIGHT EXPRESSION IN HEARTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION PATIENTS: ISCHEMIC VS. NON-ISCHEMIC ORIGIN

Introduction and objectivesMitochondrial pyruvate copyright (MPC) mediates the entry of pyruvate into mitochondria, determining whether pyruvate is incorporated equi-jec 6 into the Krebs cycle or metabolized in the cytosol.In heart failure (HF), a large amount of pyruvate is metabolized to lactate in the cytosol rather than being oxidized inside th

Tibouchina hatschbachii Wurdack (Melastomataceae) is an autogamous shrub restricted to granite (GO) and sandstone (SO) rock outcrops from subtropical Brazil.We designed primers for the amplification of microsatellite regions for T.hatschbachii, and characterized these primers to estimate genetic diversity parameters and contemporary genetic structu

Emittance is a key figure-of-merit for high brightness electron beams that enable the success of a broad range of modern accelerator-based instruments.With the successful implementation of the emittance compensation scheme and beam-shaping techniques to align each temporal beam slice in phase space, slice emittance starts to play a more dominating

Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all alarecre.com over the world.Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released by most cellular types, exert pivotal and multifaceted roles in physiology and disease.Emerging evidence emphasizes the importance of EVs in intercellular